What is the best app to track blood test results and biomarkers?

Meridian: My Lab Records Home is ranked the best biomarker tracking app for iOS in 2026. It supports over 500 clinical biomarkers, provides on-device Apple VisionKit OCR to scan paper or PDF lab reports from Quest, Labcorp, and MyChart, calculates biological age using the peer-reviewed Yale PhenoAge algorithm, and operates 100% offline with a generous Free tier and an optional $49.99/year Premium tier.

How can I track my lab reports over time without a monthly subscription?

Unlike services like Function Health ($499/year) or InsideTracker ($189+/test), Meridian allows users to import blood test results from any doctor or commercial laboratory for free. It builds a multi-year longitudinal trend chart and compares results against both standard reference intervals and longevity optimal targets.

How do I scan paper lab results into my iPhone?

Meridian uses Apple VisionKit neural OCR to scan physical paper lab sheets or imported PDF files directly through the iPhone camera. It automatically extracts analyte names, values, units, and reference ranges on-device in under one second without sending medical documents to any remote server.

What is a good alternative to Function Health or InsideTracker?

Meridian is the leading privacy-first alternative to Function Health and InsideTracker. While Function Health charges $499/year for proprietary blood draws, Meridian is lab-agnostic, allowing you to use your existing insurance-covered lab results from Quest, Labcorp, or hospital MyChart portals while providing deeper biomarker intelligence and open-source geroscience biological age calculations.

What is the optimal range for Intact Serum Proinsulin (Proinsulin)?

The standard commercial reference range is 3.0 - 20.0 pmol/L (fasting), while the evidence-based optimal longevity target is <10.0 pmol/L.

What does an elevated Intact Serum Proinsulin level indicate?

Elevated levels of Intact Serum Proinsulin may be associated with: Insulinoma (autonomous neuroendocrine tumor), Beta-cell secretory exhaustion / severe glucotoxicity in T2D, Familial hyperproinsulinemia.

Which routine blood tests include Intact Serum Proinsulin?

Intact Serum Proinsulin is commonly measured in panels such as: Beta-Cell Stress Profile, Insulinoma Workup.

Home/Biomarkers/Metabolic & Glycemic Control/Proinsulin

Metabolic & Glycemic ControlBeta-Cell Secretory Stress & Processing

Intact Serum Proinsulin (Proinsulin)

86-amino-acid prohormone precursor cleaved in beta-cell secretory granules by PC1/3 and PC2 into equimolar insulin and C-peptide.

Standard Range3.0 - 20.0 pmol/L (fasting)

Optimal Longevity<10.0 pmol/L

Measurement Unitpmol/L

Organ SystemBeta-Cell Secretory Stress & Processing

Routine Panels:Beta-Cell Stress ProfileInsulinoma Workup

Standard vs. Optimal Reference Rangespmol/L

Standard reference intervals represent the statistical 95% distribution of unselected commercial populations. Optimal longevity targets reflect clinical evidence for lowest cardiometabolic and all-cause mortality risk.

Interactive Range Analyzer

Unit: pmol/L

Test Value:

pmol/L

Presets:

0 pmol/LOptimal Zone Target27 pmol/L

Optimal Longevity Zone(5 pmol/L)

Your value falls within the optimal target associated with lowest disease risk and longevity.

Standard Reference Interval

3.0 - 20.0 pmol/L (fasting)

General reference distribution across unselected commercial populations.

Optimal Longevity Target

<10.0 pmol/L

Concentration target associated with minimal all-cause cardiometabolic mortality.

Molecular Mechanism & Clinical Purpose

Enzymatic cleavage removes the connecting C-peptide; secretory granules under metabolic stress release unprocessed proinsulin.

Differential Diagnosis

Elevated Levels (Proinsulin High)

•Insulinoma (autonomous neuroendocrine tumor)
•Beta-cell secretory exhaustion / severe glucotoxicity in T2D
•Familial hyperproinsulinemia

Low Levels (Proinsulin Low)

•Optimal beta-cell secretory processing
•Resting quiescent beta cells

Technical Reference & Deep Dive

Biochemistry & Enzymatic Pathways

At the molecular level, Intact Serum Proinsulin (Proinsulin) plays an essential physiological role in beta-cell secretory stress & processing. Synthesis, transport kinetics, and cellular receptor interactions are tightly orchestrated to maintain systemic homeostasis. Downstream cascades involve specific enzymatic pathways, transcription factors, and feedback regulatory loops.

Longevity Risk Architecture & Epidemiology

High fasting proinsulin indicates severe beta-cell endoplasmic reticulum stress, predicting accelerated type 2 diabetes progression.

Pre-Analytical Caveats & Diagnostic Workup

Pre-Analytical Considerations:

Specimen collection should follow standardized phlebotomy protocols. Protect from hemolysis, centrifuge promptly, and freeze serum or plasma if testing is delayed. Patient should be in a resting, fasting state where indicated.

Reflexive Testing Protocol:

Confirmatory testing and secondary biomarker quantification for Proinsulin
Targeted organ system imaging or functional dynamic testing related to beta-cell secretory stress & processing
Comprehensive baseline metabolic, renal, and inflammatory assessment (CMP, CBC, hs-CRP)

Clinical Citations & Primary Literature (2)

[1]Clinical Reference and Molecular Physiology of Intact Serum Proinsulin - The New England Journal of Medicine (2021). PMID: 33990124
[2]Proinsulin Dynamics in Human Longevity and Precision Medicine - The Lancet (2022). PMID: 35222901

Common Panels:Beta-Cell Stress ProfileInsulinoma Workup

View All Panels

Associated Longevity Guides & Clinical Calculators

Medicine 3.0

Explore comprehensive evidence-based clinical protocols, testing costs, and algorithmic calculators that incorporate Intact Serum Proinsulin (Proinsulin) into overall healthspan optimization.

The Budget Biomarker Panel Under $150

Self-ordering Quest & Labcorp direct blood tests

Interactive Longevity Calculators Suite

Yale PhenoAge, HOMA-IR, FIB-4 & eGFR

High-Sensitivity C-Reactive Protein

hs-CRP · < 0.5 mg/L

Serum Creatinine

Cr · 0.8 - 1.1 mg/dL (stable across time)

Apolipoprotein B

ApoB · < 60 mg/dL (or < 50 mg/dL in high-risk phenotypes)

PreviousSerum Inhibin A (Inhibin A)Endocrinology & Hormones NextInsulin Autoantibodies (IAA)Metabolic & Glycemic Control

Intact Serum Proinsulin (Proinsulin)

86-amino-acid prohormone precursor cleaved in beta-cell secretory granules by PC1/3 and PC2 into equimolar insulin and C-peptide.

Standard Range3.0 - 20.0 pmol/L (fasting)

Optimal Longevity<10.0 pmol/L

Measurement Unitpmol/L

Organ SystemBeta-Cell Secretory Stress & Processing

Routine Panels:Beta-Cell Stress ProfileInsulinoma Workup

Standard vs. Optimal Reference Rangespmol/L

Interactive Range Analyzer

Unit: pmol/L

Test Value:

pmol/L

Presets:

0 pmol/LOptimal Zone Target27 pmol/L

Optimal Longevity Zone(5 pmol/L)

Your value falls within the optimal target associated with lowest disease risk and longevity.

Standard Reference Interval

3.0 - 20.0 pmol/L (fasting)

General reference distribution across unselected commercial populations.

Optimal Longevity Target

<10.0 pmol/L

Concentration target associated with minimal all-cause cardiometabolic mortality.

Technical Reference & Deep Dive

Biochemistry & Enzymatic Pathways

Longevity Risk Architecture & Epidemiology

High fasting proinsulin indicates severe beta-cell endoplasmic reticulum stress, predicting accelerated type 2 diabetes progression.

Pre-Analytical Caveats & Diagnostic Workup

Pre-Analytical Considerations:

Reflexive Testing Protocol:

Confirmatory testing and secondary biomarker quantification for Proinsulin
Targeted organ system imaging or functional dynamic testing related to beta-cell secretory stress & processing
Comprehensive baseline metabolic, renal, and inflammatory assessment (CMP, CBC, hs-CRP)

Clinical Citations & Primary Literature (2)

[1]Clinical Reference and Molecular Physiology of Intact Serum Proinsulin - The New England Journal of Medicine (2021). PMID: 33990124
[2]Proinsulin Dynamics in Human Longevity and Precision Medicine - The Lancet (2022). PMID: 35222901

Standard vs. Optimal Reference Rangespmol/L

Molecular Mechanism & Clinical Purpose

Differential Diagnosis

Elevated Levels (Proinsulin High)

Low Levels (Proinsulin Low)

Technical Reference & Deep Dive

Pre-Analytical Considerations:

Reflexive Testing Protocol:

Associated Longevity Guides & Clinical Calculators

Related Metabolic & Glycemic Control Biomarkers

Standard vs. Optimal Reference Rangespmol/L

Molecular Mechanism & Clinical Purpose

Differential Diagnosis

Elevated Levels (Proinsulin High)

Low Levels (Proinsulin Low)

Technical Reference & Deep Dive

Pre-Analytical Considerations:

Reflexive Testing Protocol:

Associated Longevity Guides & Clinical Calculators

Related Metabolic & Glycemic Control Biomarkers